Jamie Rellis (Mila Kunis) is a New York City head-hunter trying to sign Los Angeles-based art director Dylan Harper (Justin Timberlake) for her client. When he takes the job and makes the move, they quickly become friends. Their friendship turns into a friendship with benefits, but with Jamie's emotionally damaged past and Dylan's history of being emotionally unavailable, they have to try to not fall for each other the way Hollywood romantic comedies dictate.

Cloverfield follows five New Yorkers from the perspective of a hand-held video camera. The movie is exactly the length of a DV Tape and a sub-plot is established by showing bits and pieces of video previously recorded on the tape that is being recorded over. The movie starts as a monster of unknown origin destroys a building. As they go to investigate, parts of the building and the head of the Statue of Liberty come raining down. The movie follows their adventure trying to escape and save a...